Bioactivity | Thalidomide-PEG1-OTs (Compound 5) is a ligand for E3 ligase, used for the synthesis of YD54 (HY-168221) [1]. |
CAS | 2850354-04-8 |
Formula | C22H20N2O8S |
Molar Mass | 472.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kotagiri S, et al. Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors. bioRxiv [Preprint]. 2024 Aug 26:2024.08.23.608456. |