Bioactivity | Thalidomide-O-amido-PEG2-C2-NH2 incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer. |
Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Name | Thalidomide-O-amido-PEG2-C2-NH2 |
CAS | 1957235-74-3 |
Formula | C21H26N4O8 |
Molar Mass | 462.45 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. ARYL SULFONOHYDRAZIDES. WO 2017/176958 A1. |