| Bioactivity | Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L[1]. |
| Name | Thalidomide-O-amido-C11-COOH |
| CAS | 2473270-96-9 |
| Formula | C27H35N3O8 |
| Molar Mass | 529.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jun Qi, et al. Small molecules for dot1l degradation and uses thereof. Patent WO2023069348A1. |
Thalidomide-O-amido-C11-COOH
CAS: 2473270-96-9 F: C27H35N3O8 W: 529.58
Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalido
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