| Bioactivity | Thalidomide-NH-PEG8-Ts is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 8-unit PEG linker used in PROTAC technology, such as IDO1 PROTAC degrader (HY-131911)[1]. |
| Name | Thalidomide-NH-PEG8-Ts |
| CAS | 2488761-07-3 |
| Formula | C36H49N3O14S |
| Molar Mass | 779.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hu M, et al. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1. Acta Pharm Sin B. 2020;10(10):1943-1953. |
Thalidomide-NH-PEG8-Ts
CAS: 2488761-07-3 F: C36H49N3O14S W: 779.85
Thalidomide-NH-PEG8-Ts is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cerebl
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