Bioactivity | Thalidomide-NH-C3-O-Ph(NO2)-methylester-O-pyrrolidine-2,5-dione is the conjugate of a linker and a ligand for E3 ligase. Thalidomide-NH-C3-O-Ph(NO2)-methylester-O-pyrrolidine-2,5-dione can be used for synthesis of PROTAC BRD4 Degrader-26 (HY-161650)[1]. |
Formula | C28H25N5O12 |
Molar Mass | 623.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xu H, et al., Photo-regulated PROTACs: A novel tool for temporal control of targeted protein degradation. Bioorg Med Chem Lett. 2024 Jul 15;107:129778. |