| Bioactivity | Thalidomide 5-pyrrolidine-CHO is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of NRX-0492 (HY-153357)[1]. |
| CAS | 2416132-74-4 |
| Formula | C18H17N3O5 |
| Molar Mass | 355.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang D, et al. NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts. Blood. 2023 Mar 30;141(13):1584-1596. |
Thalidomide 5-pyrrolidine-CHO
CAS: 2416132-74-4 F: C18H17N3O5 W: 355.34
Thalidomide 5-pyrrolidine-CHO is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of NRX-0492
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