Bioactivity | Thailanstatin A cyclohexane diamine formic is an analog of Spliceostatin (HY-16466). Thailanstatin A cyclohexane diamine formic inhibits proliferations of cells N87, BT474, MDA-MB-361-DYT2 and MDA-MB-468, with IC50 of 0.33, 0.34, 0.88 and 0.27 μM, respectively. Thailanstatin A cyclohexane diamine formic is used as a drug-linker conjugate for ADC molecule[1]. |
Formula | C35H55N3O10 |
Molar Mass | 677.83 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
Reference | [1]. DIRICO KJ, et al., Spliceostatin analogs. WO2014068443. |