| Bioactivity | Tezepelumab (AMG 157) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma[1]. |
| Target | TSLP |
| Invitro | Tezepelumab 阻断胸腺基质淋巴细胞生成素，一种上皮细胞衍生的细胞因子，与哮喘的发病机理有关[1]。 |
| Name | Tezepelumab |
| CAS | 1572943-04-4 |
| Appearance | Liquid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Menzies-Gow A, et, al. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809. |