Bioactivity | Tetraproline is a fragment sequence in tristetraprolin (TTP). Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements[1]. |
Name | Tetraproline |
CAS | 21866-90-0 |
Sequence | Pro-Pro-Pro-Pro |
Shortening | PPPP |
Formula | C20H30N4O5 |
Molar Mass | 406.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Fu R, et, al. Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements. RNA. 2016 Mar;22(3):373-82. |