| Bioactivity | Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. Tetrapeptide-30 can act as a tyrosinase inhibitor, lightening hyperpigmentation and evening out skin tone by reducing the amount of tyrosinase and inhibiting melanocyte activation[1]. | ||||||
| Invitro | Tetrapeptide-30 (0-10 μg/mL, 24 h) can effectively reduce UVB-induced gene expression of IL-6, TNF-α and POMC (proopiomelanocorticotropin), and also decreased IL-8 gene expression in a dose-dependent manner[1].Tetrapeptide-30 (PKEK) is highly hydrophilic and has good skin penetration in microemulsion[2]. | ||||||
| Name | Tetrapeptide-30 | ||||||
| CAS | 1036207-61-0 | ||||||
| Shortening | PKEK | ||||||
| Formula | C22H40N6O7 | ||||||
| Molar Mass | 500.59 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
||||||
| Reference | [1]. Alessandra Marini, et al. Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects. Exp Dermatol. 2012 Feb;21(2):140-6. [2]. Reinhard H H Neubert, et al. Dermal peptide delivery using enhancer moleculs and colloidal carrier systems. Part II: Tetrapeptide PKEK. Eur J Pharm Biopharm. 2018 Mar;124:28-33. |
Tetrapeptide-30
CAS: 1036207-61-0 F: C22H40N6O7 W: 500.59
Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. Tetrapeptide-30 can act as a tyrosinase in
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.