| Bioactivity | Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM[1]. |
| In Vivo | Tetrahydro-β-carboline (20 µg; i.c.v.) increases the serotonin levels in the same part of the brain in rats[1]. Animal Model: |
| Name | Tetrahydro-β-carboline |
| CAS | 16502-01-5 |
| Formula | C11H12N2 |
| Molar Mass | 172.23 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Rommelspacher H, et al. Inhibition of the reuptake of serotonin by tryptoline. Naunyn Schmiedebergs Arch Pharmacol. 1976;292(1):93-5. |