Bioactivity | Tertiapin LQ is a specific and reversible renal outer medullary potassium ROMK1 (Kir1.1) channel inhibitor[1]. |
Target | ROMK1. |
Name | Tertiapin LQ |
Sequence | Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-Leu-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridge:Cys3-Cys14, Cys5-Cys18) |
Shortening | ALCNCNRIIIPLQCWKKCGKK-NH2 (Disulfide bridge:Cys3-Cys14, Cys5-Cys18) |
Formula | C106H179N33O24S4 |
Molar Mass | 2428.02 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Siraskar B, et al. Downregulation of the renal outer medullary K(+) channel ROMK by the AMP-activated protein kinase. Pflugers Arch. 2013 Feb;465(2):233-45. |