Bioactivity | Terfenadine (Standard) is the analytical standard of Terfenadine. This product is intended for research and analytical applications. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9. |
CAS | 50679-08-8 |
Formula | C₃₂H₄₁NO₂ |
Molar Mass | 471.67 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |