Terbuthylazine-desethyl-d9_product_DataBase

Bioactivity	Terbuthylazine-desethyl-d9 is the deuterium labeled Terbuthylazine-desethyl[1]. Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide)[2][3].
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	Terbuthylazine-desethyl-d9
CAS	1219798-52-3
Formula	C7H3D9ClN5
Molar Mass	210.71
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Potter TL, et, al. Tillage, cover-crop residue management, and irrigation incorporation impact on fomesafen runoff. J Agric Food Chem. 2011 Jul 27;59(14):7910-5. [3]. Navarro S, et, al. Determination of simazine, terbuthylazine, and their dealkylated chlorotriazine metabolites in soil using sonication microextraction and gas chromatography. J AOAC Int. Sep-Oct 200083(5):1239-43.

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