| Bioactivity | Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties. | ||||||||||||
| Invitro | Tenoxicam (Ro-12-0068) is a non-steroidal anti-inflammatory drug (NSAID)[1]. | ||||||||||||
| In Vivo | Tenoxicam (Ro-12-0068) was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam (Ro-12-0068) treatment. Tenoxicam (Ro-12-0068) also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia[2]. | ||||||||||||
| Name | Tenoxicam | ||||||||||||
| CAS | 59804-37-4 | ||||||||||||
| Formula | C13H11N3O4S2 | ||||||||||||
| Molar Mass | 337.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Ozgocmen, S., et al., In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis. Ann Clin Lab Sci, 2005. 35(2): p. 137-43. [2]. Galvao, R.I., et al., Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats. Neurochem Res, 2005. 30(1): p. 39-46. |