| Bioactivity | Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity[1]. |
| In Vivo | Temocillin dosing regimens of 200 mg/kg every 4 and 6 h remained significantly effective in reducing bacterial titres in kidneys against the two strains, with no significant difference between the parental strain and its transconjugant[2]. |
| Name | Temocillin disodium |
| CAS | 61545-06-0 |
| Formula | C16H16N2Na2O7S2 |
| Molar Mass | 458.42 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture) |
| Reference | [1]. K Jules, et al. Antibacterial activity and beta-lactamase stability of temocillin. Antimicrob Agents Chemother. 1982 Sep;22(3):453-60. [2]. J F Soubirou, et al. Activity of temocillin in a murine model of urinary tract infection due to Escherichia coli producing or not producing the ESBL CTX-M-15. J Antimicrob Chemother. 2015 May;70(5):1466-72. |