Bioactivity | Telomerase-IN-4 is a potent telomerase inhibitor. Telomerase-IN-4 has antiproliferative activity and induces apoptosis[1]. |
Invitro | Telomerase-IN-4 (compound 8e; 0.1-100 μg/mL; 72 h) 对两种癌细胞系都有抗肿瘤作用,对 MCF-7 和 A549 细胞的 IC50 值分别为 9.47 和 17.09 μg/mL[1]。Telomerase-IN-4 (9.467 μg/mL; 48 h) 将细胞周期阻滞在 S 期,诱导 MCF-7 细胞凋亡[1]。 Cell Viability Assay[1] Cell Line: |
Name | Telomerase-IN-4 |
Formula | C21H18N4OS2 |
Molar Mass | 406.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |