Bioactivity | Teleocidin B-4 is a PKC activator. Teleocidin B-4 can promote the accumulation of HIF-1α protein and upregulate hypoxia-inducible factor 1 (HIF-1) activity through a PKC activator via the PKCα/mTORC signaling pathway. Teleocidin B-4 can be used in cancer-related research[1]. |
CAS | 11032-05-6 |
Formula | C28H41N3O2 |
Molar Mass | 451.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Iseki S, et al. Teleocidin B-4, a PKC Activator, Upregulates Hypoxia-Inducible Factor 1 (HIF-1) Activity by Promoting the Accumulation of HIF-1α Protein via the PKCα/mTORC Signaling Pathway. J Nat Prod. 2024 Jun 28;87(6):1666-1671. |