| Bioactivity | Tec-IN-1 (Compound 21) is a Tec inhibitor (IC50s of 11.7 μM). Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation of FGF2, and inhibits FGF2 secretion from cells[1]. |
| Target | 11.7 μM (Tec) |
| Name | Tec-IN-1 |
| CAS | 931664-41-4 |
| Formula | C16H15ClN4O2S |
| Molar Mass | 362.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. La Venuta G, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291(34):17787-803. |
Tec-IN-1
CAS: 931664-41-4 F: C16H15ClN4O2S W: 362.83
Tec-IN-1 (Compound 21) is a Tec inhibitor (IC50s of 11.7 μM). Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation o
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