| Bioactivity | Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa. | ||||||||||||
| Invitro | Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin, and apparent Km and kcat values of 0.8 μM and 0.03 min-1, respectively[1]. Tebipenem shows potent activity against B. pseudomallei, with MIC50 and MIC90 values of both 2 mg/L[2]. Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates[3]. | ||||||||||||
| Name | Tebipenem | ||||||||||||
| CAS | 161715-21-5 | ||||||||||||
| Formula | C16H21N3O4S2 | ||||||||||||
| Molar Mass | 383.49 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Tebipenem
CAS: 161715-21-5 F: C16H21N3O4S2 W: 383.49
Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negativ
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