| Bioactivity | TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM)[1]. |
| Target | IC50: TbPTR1) |
| Name | TbPTR1 inhibitor 1 |
| CAS | 2499713-65-2 |
| Formula | C22H21N7O |
| Molar Mass | 399.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pöhner I, et al. Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J Med Chem. 2022 Jun 8. |
TbPTR1 inhibitor 1
CAS: 2499713-65-2 F: C22H21N7O W: 399.45
TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50
Data collection：peptidedb@qq.com
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