| Bioactivity | Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma[1][2][3]. | ||||||||||||
| In Vivo | Assessment of Pharmacokinetics (PK) profile of Tazarotenic acid (Compound AGN 190299) after an intravenous of AGN 190168 in rats[1]. | ||||||||||||
| Name | Tazarotenic acid | ||||||||||||
| CAS | 118292-41-4 | ||||||||||||
| Formula | C19H17NO2S | ||||||||||||
| Molar Mass | 323.41 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Chandraratna RA. Tazarotene--first of a new generation of receptor-selective retinoids. Br J Dermatol. 1996;135 Suppl 49:18-25. [2]. Hsyu PH, et al. Pharmacokinetics of a novel retinoid AGN 190168 and its metabolite AGN 190299 after intravenous administration of AGN 190168 to rats. Biopharm Drug Dispos. 1994;15(5):347-357. [3]. Abramovits W, et al. Treatment of warty dyskeratoma with tazarotenic acid. J Am Acad Dermatol. 2002;46(2 Suppl Case Reports):S4. |
Tazarotenic acid
CAS: 118292-41-4 F: C19H17NO2S W: 323.41
Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the prob
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