Bioactivity | Taxuspine B is a natural product, that can be isolated from Japanese yew Taxus. Taxuspine B exhibits appreciable taxol-like activity to reduce CaCl2-induced depolymerixation of microtubules among the taxoids[1]. |
Invitro | Taxuspine B 对小鼠淋巴瘤 L1210 (IC50=18 μg/mL) 和人表皮样癌 KB 细胞表现出较弱的细胞毒性,在 10 μg/mL 时抑制率分别为 42.3% 和 11.8% [1]。 |
Name | Taxuspine B |
CAS | 157414-05-6 |
Formula | C35H42O10 |
Molar Mass | 622.70 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Juníchi Kobayashi, et al. Taxuspines A-C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells. 1994, 50(25):7401-7416. |