| Bioactivity | Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significantprotective effects in LPS-induced acute lung injury in mice[1][2]. |
| Name | Taxamairin B |
| CAS | 110300-77-1 |
| Formula | C22H24O4 |
| Molar Mass | 352.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu M, et al. Rapid access to icetexane diterpenes: Their protective effects against lipopolysaccharides-induced acute lung injury via PI3K/AKT/NF-κB axis in macrophages. Eur J Med Chem. 2023 Nov 15;260:115769. [2]. Liang JY, et al. Two new antineoplastic diterpenes from Taxus mairei. Chem Pharm Bull (Tokyo). 1987 Jun;35(6):2613-4. |