| Bioactivity | Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist[1]. |
| Invitro | Taurolithocholic acid (TLCA) at low concentrations (5 µM) tends to selectively increase the membrane-associated fraction of the e-isoform of PKC by 44.1% ± 40.2%[1].TLCA (10 µM) selectively induces translocation of theε-isoform of PKC to the hepatocellular membranes, a key step for activation of mobile PKC isoforms[1]. |
| Name | Taurolithocholic acid sodium salt |
| CAS | 6042-32-6 |
| Formula | C26H44NNaO5S |
| Molar Mass | 505.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |