Tat-βsyn-degron

CAS: 2816095-52-8 F: C132H237N59O31 W: 3146.67

Tat-βsyn-degron is an α-synuclein knockdown peptide. Tat-βsyn-degron binds toα-synuclein and reduces α-synuclein le

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Bioactivity	Tat-βsyn-degron is an α-synuclein knockdown peptide. Tat-βsyn-degron binds toα-synuclein and reduces α-synuclein levels in primary rat cortical neuron cultures. Tat-βsyn-degron also reduces α-synuclein levels and decreases the parkinsonian toxin-induced neuronal damage and motor impairment in a mouse toxicity model of PD[1].
CAS	2816095-52-8
Sequence	Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Thr-Lys-Ser-Gly-Val-Tyr-Leu-Val-Gly-Arg-Arg-Arg-Gly
Shortening	YGRKKRRQRRRRTKSGVYLVGRRRG
Formula	C132H237N59O31
Molar Mass	3146.67
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Jin JW, et al. Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson's disease models. Commun Biol. 2021 Feb 19;4(1):232.

Oligopeptide P11-4

Synapsin I-(3-13)