| Bioactivity | Taltobulin intermediate-12 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1]. |
| Name | Taltobulin intermediate-12 |
| Formula | C12H15NO3 |
| Molar Mass | 221.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45. |
Taltobulin intermediate-12
CAS: F: C12H15NO3 W: 221.25
Taltobulin intermediate-12 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin co
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