| Bioactivity | PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2). |
| Invitro | PF-07104091 hydrate (Example 13) inhibits CDK1/cyclin A2, CDK4/cyclin D1, CDK6/cyclin D3 and CDK9, with Kis of 110, 238, 465 and 117 nM, respectively[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Tagtociclib hydrate 相关抗体: |
| CAS | 2733575-91-0 |
| Formula | C19H30N6O5 |
| Molar Mass | 422.48 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Douglas Carl BEHENNA, et al. Cdk2 inhibitors. WO2020157652A2. |
Tagtociclib hydrate
CAS: 2733575-91-0 F: C19H30N6O5 W: 422.48
PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respe
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.