Bioactivity | Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1]. |
Name | Tachyplesin I |
CAS | 118231-04-2 |
Sequence | Lys-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Arg-Cys-Arg-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12) |
Shortening | KWCFRVCYRGICYRRCR-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12) |
Formula | C99H151N35O19S4 |
Molar Mass | 2263.74 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. D V Kuzmin, et al. In Vitro Study of Antitumor Effect of Antimicrobial Peptide Tachyplesin I in Combination with Cisplatin. Bull Exp Biol Med. 2018 Jun;165(2):220-224. |