| Bioactivity | Tabituximab (OTSA101) is a humanized monoclonal antibody against frizzled class receptor 10 (FZD10)[1]. |
| Target | FZD10 |
| Invitro | 非放射标记的 Tabituximab (OTSA101) 抗体对滑膜肉瘤细胞生长只有较弱的拮抗活性[1]。 |
| In Vivo | Yttrium 90 放射标记的 OTSA101 (OTSA101-DTPA-90Y) 在小鼠异种移植模型静脉单次注射后显示出显著的抗肿瘤活性[1]。 |
| Name | Tabituximab |
| CAS | 1644134-10-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Blagodatski A, et al. Targeting the Wnt pathways for therapies. Mol Cell Ther. 2014 Sep 11;2:28. |