| Bioactivity | TXA707, the active metabolite of TXA-709, is an FtsZ inhibitor with antibacterial activity. TXA707 is promising for research of S. aureus infections[1][2]. | ||||||||||||
| CAS | 1609670-89-4 | ||||||||||||
| Formula | C15H8F5N3O2S | ||||||||||||
| Molar Mass | 389.30 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Lepak AJ, et al. In Vivo Pharmacodynamic Evaluation of an FtsZ Inhibitor, TXA-709, and Its Active Metabolite, TXA-707, in a Murine Neutropenic Thigh Infection Model. Antimicrob Agents Chemother. 2015 Oct;59(10):6568-74. [2]. Kaul M, et al. TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2015 Aug;59(8):4845-55. |
TXA707
CAS: 1609670-89-4 F: C15H8F5N3O2S W: 389.30
TXA707, the active metabolite of TXA-709, is an FtsZ inhibitor with antibacterial activity. TXA707 is promising for rese
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