| Bioactivity | TWEAK-Fn14-IN-1 (Compound L524-0366) is a specific dose-dependent TWEAK-Fn14 inhibitor. TWEAK-Fn14-IN-1 binds specifically to the Fn14 surface with a KD of 7.12 μM. TWEAK-Fn14-IN-1 inhibits TWEAK induced glioma cell migration without any potential cytotoxic effects[1]. |
| Target | TWEAK-Fn14 |
| CAS | 951612-19-4 |
| Formula | C13H13ClN4OS |
| Molar Mass | 308.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tran N, et al. Compositions and methods of screening for compounds that modulate activity at a tweak binding site on a crd of fn14. US20160146784A1 |
TWEAK-Fn14-IN-1
CAS: 951612-19-4 F: C13H13ClN4OS W: 308.79
TWEAK-Fn14-IN-1 (Compound L524-0366) is a specific dose-dependent TWEAK-Fn14 inhibitor. TWEAK-Fn14-IN-1 binds specifical
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