| Bioactivity | TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region[1]. |
| Invitro | TTX-P (10 μM) 对碱性磷酸酶 (ALP) 有反应，并相应地发出适合成像的 NIR-II 荧光信号（在 920 nm）[1]。TTX-P (10 μM; HepG2、4T1 和 LO2 细胞) 可以检测和监测癌细胞中 ALP 的活性[1]。 |
| In Vivo | TTX-P (5 mg/kg; 瘤内注射; 4T1 细胞异种移植 BALB/C 裸鼠) 具有检测和监测体内内源性碱性磷酸酶活性的能力[1]。 Animal Model: |
| Name | TTX-P |
| Formula | C46H35N4O5PS |
| Molar Mass | 786.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zi KC, et, al. Visualizing Detection of Diabetic Liver Injury by a Biomarker-Activatable Probe via NIR-II Fluorescence Imaging. Chem. Biomed. Imaging 2023. |