| Bioactivity | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. | ||||||||||||
| Invitro | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM[1]. | ||||||||||||
| Name | TTP 22 | ||||||||||||
| CAS | 329907-28-0 | ||||||||||||
| Formula | C16H14N2O2S2 | ||||||||||||
| Molar Mass | 330.42 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Golub AG, et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem. 2011 Mar;46(3):870-6. |