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| Bioactivity |
TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. |
| Invitro |
TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM[1]. |
| Name |
TTP 22 |
| CAS |
329907-28-0 |
| Formula |
C16H14N2O2S2 |
| Molar Mass |
330.42 |
| Appearance |
Solid |
| Transport |
Room temperature in continental US; may vary elsewhere. |
| Storage |
| Powder |
-20°C |
3 years |
|
4°C |
2 years |
| In solvent |
-80°C |
6 months |
|
-20°C |
1 month |
|
| Reference |
[1]. Golub AG, et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem. 2011 Mar;46(3):870-6. |
