| Bioactivity | TTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease[1]. | |||||||||
| Target | T-type Ca2+ channel | |||||||||
| Invitro | TTA-Q6 is a selective T-type Ca2+ channel antagonist, with 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay[1]. | |||||||||
| Name | TTA-Q6 | |||||||||
| CAS | 910484-28-5 | |||||||||
| Formula | C20H15ClF3N3O | |||||||||
| Molar Mass | 405.80 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Schlegel KA, et al. Discovery and expanded SAR of 4,4-disubstituted quinazolin-2-ones as potent T-type calcium channel antagonists. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5147-52. |