| Bioactivity | TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss[1]. | ||||||||||||
| Invitro | TT-10 (48 h) markedly promotes cell cycle activation and increased cell division of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hiPSCMs)[1]. | ||||||||||||
| Name | TT-10 | ||||||||||||
| CAS | 2230640-94-3 | ||||||||||||
| Formula | C11H10FN3OS2 | ||||||||||||
| Molar Mass | 283.35 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Masamichi Ito, et al. Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2019 Mar;128:90-95. |