| Bioactivity | TSC26, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 175 nM, a pIC50 of 6.76 and a pKa of 6.6. TSC26 has the potential for parasitic diseases research[1]. |
| Name | TSC26 |
| Formula | C13H13Cl2N5S |
| Molar Mass | 342.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gabriel Jasinski, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345. |