Bioactivity | TREM2-IN-1 is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 is capable of relievingimmunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency[1]. |
Target | TREM2 |
Name | TREM2-IN-1 |
CAS | 2000236-36-0 |
Formula | C46H68N2O20Pt |
Molar Mass | 1164.12 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yang T, et al. Platinum-Based TREM2 Inhibitor Suppresses Tumors by Remodeling the Immunosuppressive Microenvironment. Angew Chem Int Ed Engl. 2023 Jan 9;62(2):e202213337. |