| Bioactivity | TREM-1 inhibitory peptide M3 is a ligand-dependent TREM-1 antagonist. TREM-1 inhibitory peptide M3 can inhibit systemic and pulmonary pro-inflammatory cytokine and chemokine production and attenuate acute lung injury[1]. |
| Name | TREM-1 inhibitory peptide M3 |
| Sequence | Arg-Gly-Phe-Phe-Arg-Gly-Gly |
| Shortening | RGFFRGG |
| Formula | C36H53N13O8 |
| Molar Mass | 795.89 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Denning NL, et, al. Inhibition of a triggering receptor expressed on myeloid cells-1 (TREM-1) with an extracellular cold-inducible RNA-binding protein (eCIRP)-derived peptide protects mice from intestinal ischemia-reperfusion injury. Surgery. 2020 Sep;168(3):478-485. |
TREM-1 inhibitory peptide M3
CAS: F: C36H53N13O8 W: 795.89
TREM-1 inhibitory peptide M3 is a ligand-dependent TREM-1 antagonist. TREM-1 inhibitory peptide M3 can inhibit systemic
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