| Bioactivity | TPPS can be used as a non-cytotoxic probe for detecting tumor location[1]. | ||||||||||||
| Invitro | TPPS (0-20 μg/mL) shows no toxicity in Vero and HEp-2 cells in vitro and predominantly locates in the soluble and protein fractions in cells[1]. | ||||||||||||
| In Vivo | TPPS4 shows the highest tumor to tissue ratios after 96 hours injection with a dose dependent manner[2].TPPS4 appears to be cleared through the kidneys and absolute concentrations there are reduced with increasing time after injection[2]. | ||||||||||||
| Name | TPPS | ||||||||||||
| CAS | 35218-75-8 | ||||||||||||
| Formula | C44H30N4O12S4 | ||||||||||||
| Molar Mass | 934.99 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Austen JD, et al. Intracellular localization of meso-Tetra(p-sulfophenyl)porphine: a potential tumor localizing agent. Cancer Treat Rep. 1978 Apr;62(4):511-8. [2]. https://pubmed.ncbi.nlm.nih.gov/201378/ |