| Bioactivity | TPA-dT is a thymidine analog with a tris[(2-pyridyl)methyl]amine (TPA) group. TPA-dT can be used to modify siRNAs. The TPA-modified siRNAs remain functionally inactive and is incapable of silencing gene expression until the TPA moiety is removed upon exposure to Cu(I)[1]. |
| Formula | C29H32N6O5 |
| Molar Mass | 544.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Morihiro K, et al. Copper-mediated siRNA activation for conditional control of gene expression. Bioorg Med Chem Lett. 2024 May 15;104:129738. |