Bioactivity | TP0628103 (compound 18) is a selective inhibitor of MMP-7, with the IC50 value of 0.17 nM that plays an important role in cancer and fibrosis[1]. |
Name | TP0628103 |
CAS | 2865102-08-3 |
Formula | C51H67ClF3N11O11S |
Molar Mass | 1134.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yusuke Oka, et al. Discovery of TP0628103: A Highly Potent and Selective MMP-7 Inhibitor with Reduced OATP-Mediated Clearance Designed by Shifting Isoelectric Points. J Med Chem. 2024 Jan 12. doi: 10.1021/acs.jmedchem.3c01967. |