| Bioactivity | TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min)[1]. |
| Invitro | TP0597850 (化合物 18) 在广谱 pH 值下表现出极高的化学稳定性[1]。TP0597850 的抑制常数 Ki 值为 0.034 nM[1]。 |
| Name | TP0597850 |
| CAS | 2642181-22-2 |
| Formula | C41H57N9O13S |
| Molar Mass | 916.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Takeuchi T, et al. Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase-2 Inhibitor with a Phenylbenzamide-Pentapeptide Hybrid Scaffold. J Med Chem. 2023 Jan 12;66(1):822-836. |
TP0597850
CAS: 2642181-22-2 F: C41H57N9O13S W: 916.01
TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 mi
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