TP0586532_product_DataBase

CAS: 2427584-96-9 F: C26H28N4O4 W: 460.52

TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk t

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].

Target

IC50: 0.101 μM (non-hydroxamate LpxC)

Invitro

TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].

Name

TP0586532

CAS

2427584-96-9

Formula

C26H28N4O4

Molar Mass

460.52

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.

PeptideDB

TP0586532

CAS: 2427584-96-9 F: C26H28N4O4 W: 460.52