| Bioactivity | TP receptor antagonist-1 (compound 7m) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 9.46 μM for TPa and 8.49 μM for TPb, respectively. TP receptor antagonist-1 can be used for the research of cardiovascular disease[1]. |
| Invitro | TP receptor antagonist-1 (compound 7m) (10-5-10-7 M, 3 min) 在人体外血小板聚集实验中表现出抑制作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> TP receptor antagonist-1 相关抗体: |
| CAS | 1448452-21-8 |
| Formula | C17H16ClN3O4S |
| Molar Mass | 393.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bambi-Nyanguile SM, et al. Synthesis and pharmacological evaluation of 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as novel thromboxane A₂ receptor antagonists. Eur J Med Chem. 2013 Jul;65:32-40. |