| Bioactivity | TP-004 is a potent and reversible inhibitor of methionine aminopeptidase 2 (MetAP2), with an IC50 of 6 nM[1]. | ||||||||||||
| Target | IC50: 6 nM (MetAP2) | ||||||||||||
| Name | TP-004 | ||||||||||||
| CAS | 1454299-21-8 | ||||||||||||
| Formula | C17H16F3N5O | ||||||||||||
| Molar Mass | 363.34 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Cheruvallath, Z., et al. Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1. Bioorganic & Medicinal Chemistry Letters, 26(12), 2774–2778. |