| Bioactivity | TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1]. | ||||||||||||
| Target | IC50: 0.55 µM (IP6K1), 10.2 μM (IP3K). | ||||||||||||
| Name | TNP | ||||||||||||
| CAS | 519178-28-0 | ||||||||||||
| Formula | C20H16F3N7O2 | ||||||||||||
| Molar Mass | 443.38 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901. |