| Bioactivity | TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1]. |
| Target | IC50: 1.3337 μM (TNIK) |
| Invitro | TNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells[1]. |
| Name | TNIK-IN-2 |
| CAS | 2754265-76-2 |
| Formula | C22H19N3O3 |
| Molar Mass | 373.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li Y, et, al. Discovery of 3,4-Dihydrobenzo[ f][1,4]oxazepin-5(2 H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects. J Med Chem. 2022 Jan 5. |