| Bioactivity | TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα (KD = 6.8 nM). |
| Name | TNF-α-IN-6 |
| CAS | 2699704-20-4 |
| Formula | C26H25N9O2 |
| Molar Mass | 495.54 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Dietrich JD, et al. Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design. J Med Chem. 2021 Jan 14;64(1):417-429. |