| Bioactivity | TMX-4153, a bivalent degrader capable of rapidly and selectively degrading endogenous PIP4K2C with a KD value of 42 nM[1]. |
| Target | PIP4K2C. |
| Invitro | TMX-4153 (0.01, 0.05, 0.1, 0.5, 1 µM; 6 h) 在 MOLT4 中选择性降解 PIP4K2C[1]。 Western Blot Analysis[1] Cell Line: |
| Name | TMX-4153 |
| CAS | 2867519-91-1 |
| Formula | C59H67ClN10O6S |
| Molar Mass | 1079.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Teng M, et al. Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader. Angew Chem Int Ed Engl. 2023 Apr 24;62(18):e202302364. |
TMX-4153
CAS: 2867519-91-1 F: C59H67ClN10O6S W: 1079.74
TMX-4153, a bivalent degrader capable of rapidly and selectively degrading endogenous PIP4K2C with a KD value of 42 nM.
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